Look AHEAD provides insights on the role of genes in weight loss

September 3rd, 2015 by MorganDowney Leave a reply »

While the Look AHEAD Clinical Trial was discontinued some time ago, and while some the interpretations of the study remain controversial, continuing studies are showing some interesting interactions between behavior and genes. Jeanne Mc Caffery and colleagues have published one study showing that variations in the FTO and BDNF genes predicted weight regain across treatment arms.  Another study from a number of over-lapping researchers shows that variations in genes can affect the frequency of eating episodes and their composition as well. Click here for Dr. Arya Sharma’s recent post on a landmark study establishing how the FTO gene works.